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Merck
CN

G1792

Sigma-Aldrich

GITR Ligand human

>97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder

Synonym(s):

GITRL, Glucocorticoid-induced TNF ligand

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About This Item

MDL number:
MFCD03456939
UNSPSC Code:
51111800

Key Documents

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biological source

human

recombinant

expressed in baculovirus infected Sf21 cells

Assay

>97% (SDS-PAGE)

form

lyophilized powder

mol wt

14-16 kDa by SDS-PAGE (triplet)
calculated mol wt 15 kDa

storage condition

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

impurities

endotoxin, tested

UniProt accession no.

Q9UNG2

storage temp.

−20°C

Gene Information

human ... TNFSF18(8995)

Biochem/physiol Actions

Appears to act in conjunction with the GITR, to protect T cells against activation induced cell death.
Type II transmembrane protein in the TNF superfamily. Appears to act in conjunction with the GITR, to protect T cells against activation induced cell death.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 1.25 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to bind human GITR.

Other Notes

N-terminal histidine-tagged extracellular domain.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
110M1265
097K1130
091K0332
067K1234

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