G1876
L-Glutamic acid γ-ethyl ester
Synonym(s):
L-Glutamic acid 5-ethyl ester
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About This Item
Linear Formula:
C2H5OCOCH2CH2CH(NH2)COOH
CAS Number:
Molecular Weight:
175.18
Beilstein:
1725589
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
application(s)
peptide synthesis
storage temp.
−20°C
SMILES string
CCOC(=O)CC[C@H](N)C(O)=O
InChI
1S/C7H13NO4/c1-2-12-6(9)4-3-5(8)7(10)11/h5H,2-4,8H2,1H3,(H,10,11)/t5-/m0/s1
InChI key
XMQUEQJCYRFIQS-YFKPBYRVSA-N
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Functional organization of presynaptic metabotropic glutamate receptors in vagal brainstem circuits.
Kirsteen N Browning et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(34), 8979-8988 (2007-08-24)
We demonstrated previously that, by suppressing cAMP levels, metabotropic glutamate receptors (mGluRs) play a crucial role in opioid receptor trafficking on GABAergic nerve terminals within gastric brainstem vagal circuits. Using whole-cell patch-clamp recordings, we aimed to correlate the influence of
Jingyi Ma et al.
Behavioural brain research, 133(1), 45-56 (2002-06-06)
The involvement of metabotropic glutamate receptor (mGluR) subtypes in the generation of hippocampal EEG (30-100 Hz) and behaviors induced by a hippocampal afterdischarge (AD) was examined in freely behaving rats. A hippocampal AD induced an increase in gamma waves (30-100
V M Kozhanov et al.
Tsitologiia, 46(4), 326-336 (2004-09-07)
The role of group II metabotropic glutamate receptors (mGluRs) in modulation of inhibitory synaptic activity was studied by intracellular recording of motoneuron miniature inhibitory spontaneous postsynaptic potentials (mIPSPs) in isolated lumbar segments of the turtle spinal cord in the medium
Alison Berent Spillson et al.
Experimental neurology, 184 Suppl 1, S97-105 (2003-11-05)
The metabotropic glutamate receptors (mGluRs) are a family of glutamate-sensitive receptors that regulate neuronal function separately from the ionotropic glutamate receptors. By coupling to guanosine nucleotide-binding proteins (G proteins), mGluRs are able to regulate neuronal injury and survival, likely through
P M B Cahusac et al.
Neuroscience, 146(1), 202-212 (2007-03-10)
Group II metabotropic (mGlu) receptors are known to play an important role in regulating the release of excitatory transmitter in a number of brain areas. Previous experiments demonstrated that (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) depressed excitatory transmission in the adult rat barrel
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