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G21200-HH

DMT-2′O-TBDMS-rG(tac) Phosphoramidite

Name: DMT-2′O-TBDMS-rG(tac) Phosphoramidite
Brand: SIGMA

Synonym(s):

DMT-2′-O-TBDMS-rG(tac) amidite, N-[[4-(1,1-dimethylethyl)phenoxy]acetyl]-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-guanosine,3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

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About This Item

Empirical Formula (Hill Notation):

C₅₈H₇₆N₇O₁₀PSi

CAS Number:

149989-68-4

Molecular Weight:

1090.32

UNSPSC Code:

41116105

PubChem Substance ID:

329799882

MDL number:

MFCD09842116

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Properties

product line

Proligo Reagents

assay

≥98% (³¹P-NMR), ≥98.0% (reversed phase HPLC)

technique(s)

oligo synthesis: suitable

λ

conforms (UV/VIS Identity)

nucleoside profile

base: guanosine
base protecting group: TAC
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: fast

storage temp.

−20°C

SMILES string

COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4C(=O)NC(NC(=O)COc5ccc(cc5)C(C)(C)C)=Nc34)(c6ccccc6)c7ccc(OC)cc7

InChI

1S/C58H76N7O10PSi/c1-38(2)65(39(3)4)76(72-34-18-33-59)74-50-47(35-71-58(41-19-16-15-17-20-41,42-23-27-44(68-11)28-24-42)43-25-29-45(69-12)30-26-43)73-54(51(50)75-77(13,14)57(8,9)10)64-37-60-49-52(64)62-55(63-53(49)67)61-48(66)36-70-46-31-21-40(22-32-46)56(5,6)7/h15-17,19-32,37-39,47,50-51,54H,18,34-36H2,1-14H3,(H2,61,62,63,66,67)/t47-,50-,51-,54-,76?/m1/s1

InChI key

ODCBQUOWLVQKQG-PZUNXSRFSA-N

Description

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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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