G2420
Anti-G Protein-Coupled Receptor BG37/TGR5 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-GPCR BG37/TGR5
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About This Item
UNSPSC Code:
12352203
MDL number:
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... GPBAR1(151306)
mouse ... Gpbar1(227289)
rat ... Gpbar1(338443)
Immunogen
synthetic peptide corresponding to the C-terminal domain of human G protein-coupled receptor BG37/TGR5, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse genes.
Physical form
Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Instructions
Yuji Kawamata et al.
The Journal of biological chemistry, 278(11), 9435-9440 (2003-01-14)
So far some nuclear receptors for bile acids have been identified. However, no cell surface receptor for bile acids has yet been reported. We found that a novel G protein-coupled receptor, TGR5, is responsive to bile acids as a cell-surface
Takaharu Maruyama et al.
Biochemical and biophysical research communications, 298(5), 714-719 (2002-11-07)
Bile acids play an essential role in the solubilization and absorption of dietary fat and lipid-soluble vitamins. Bile acids also modulate the transcription of various genes for enzymes and transport proteins for their own and cholesterol homeostasis through binding to