G5798
[10]-Gingerol
≥98% (HPLC)
Synonym(s):
(S)- 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone, 10-Gingerol
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About This Item
Empirical Formula (Hill Notation):
C21H34O4
CAS Number:
Molecular Weight:
350.49
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
Quality Segment
assay
≥98% (HPLC)
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
CCCCCCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1
InChI
1S/C21H34O4/c1-3-4-5-6-7-8-9-10-18(22)16-19(23)13-11-17-12-14-20(24)21(15-17)25-2/h12,14-15,18,22,24H,3-11,13,16H2,1-2H3/t18-/m0/s1
InChI key
AIULWNKTYPZYAN-SFHVURJKSA-N
General description
[10]-Gingerol is a pungent, non-volatile phenolic compound of fresh ginger root.
Application
[10]-Gingerol has been used as an antibacterial agent to study its effects on Escherichia coli ATP synthase. It has also been used as an anti-hyperglycemic agent to test its effects on promoting glucose utilization in 3T3-L1 adipocytes and C2C12 myotubes.
Biochem/physiol Actions
[10]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity.
[10]-Gingerol is a potent anti-cancer agent and a known inhibitor of breast cancer cells growth by blocking cell proliferation and inducing programmed cell death. It also inhibits ovarian cancer cells growth by inducing G2 phase cell cycle arrest. 10-Gingerol elicits inhibitory effects towards triple breast cancer cells in both mouse models and in vitro studies. It also displays anti-neuroinflammatory and anti-hyperglycemic activities.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
331.3 °F - closed cup
flash_point_c
166.3 °C - closed cup
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