G6014
rac-Glycerol 1-phosphate disodium salt hydrate
≥75% (enzymatic)
Synonym(s):
DL-α-Glycerophosphate disodium salt hydrate
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About This Item
Empirical Formula (Hill Notation):
C3H7Na2O6P · xH2O
CAS Number:
Molecular Weight:
216.04 (anhydrous basis)
PubChem Substance ID:
UNSPSC Code:
12352201
Beilstein/REAXYS Number:
5177716
MDL number:
SMILES string
O.[Na+].[Na+].OCC(O)COP([O-])([O-])=O
InChI
1S/C3H9O6P.2Na.H2O/c4-1-3(5)2-9-10(6,7)8;;;/h3-5H,1-2H2,(H2,6,7,8);;;1H2/q;2*+1;/p-2
InChI key
OFNNKPAERNWEDD-UHFFFAOYSA-L
assay
≥75% (enzymatic)
impurities
~6 mol/mol water
storage temp.
2-8°C
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Application
rac-Glycerol 1-phosphate does not affect the growth and metabolism of E. coli at concentrations of 5-100μm.
Biochem/physiol Actions
rac-Glycerol 1-phosphate was shown to be produced in mammalian tissues by the hydrolysis of rac-glycerol 1:2-cyclic phosphate by a soluble phosphodiesterase.
Analysis Note
The main impurity is β-glycerophosphate.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Heidi C Dodson et al.
The Journal of biological chemistry, 286(38), 33150-33157 (2011-08-05)
The African trypanosome, Trypanosoma brucei, compartmentalizes some metabolic enzymes within peroxisome-like organelles called glycosomes. The amounts, activities, and types of glycosomal enzymes are modulated coincident with developmental and environmental changes. Pexophagy (fusion of glycosomes with acidic lysosomes) has been proposed
Michele Alves-Bezerra et al.
Biochimica et biophysica acta, 1821(12), 1462-1471 (2012-08-21)
Although triacylglycerol (TAG) stores play a critical role in organisms, mechanisms underlying TAG synthesis are poorly understood in invertebrates. In mammals, the synthesis of glycerolipids, including TAG, diacylglycerol (DAG) and phospholipids (PL), occurs predominantly by the glycerol-3-phosphate (G3P) pathway in
Jean-Louis Gallis et al.
Pharmacological research, 65(3), 387-395 (2012-01-10)
The effects of trans-resveratrol (RSV) combined with ethanol (EtOH) were evaluated by (31)P NMR on total ATP and sn-glycerol-3-phosphate (sn-G3P) contents measured in real time in isolated and perfused whole liver of the rat. Mitochondrial ATP turnover was assessed by
Haruo Shimada et al.
Biochemistry, 50(19), 4114-4120 (2011-04-09)
The structure of membrane lipids in Archaea is different from those of Bacteria and Eucarya in many ways including the chirality of the glycerol backbone. Until now, heterochiral membranes were believed to be unstable; thus, no cellular organism could have
Sanjeewa Gamagedara et al.
Bioanalysis, 4(10), 1175-1183 (2012-06-02)
Urinary metabolomic profiles have recently drawn a lot of attention owing to a debate regarding their possible role as potential clinical markers for prostate cancer. In this study, levels of proline, kynurenine, uracil and glycerol-3-phosphate in 126 patients with genitourinary
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