G7522
3-α-Galactobiose
synthetic, ≥90%
Synonym(s):
α-D-Gal-(1→3)-D-Gal, 3-O-α-D-Galactopyranosyl-D-galactose
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About This Item
Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
Beilstein:
83008
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
biological source
synthetic
Assay
≥90%
storage temp.
2-8°C
SMILES string
OC[C@H]1O[C@H](O[C@@H]2[C@@H](O)C(O)O[C@H](CO)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1O
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Gisella L Puga Yung et al.
Xenotransplantation, 19(3), 196-206 (2012-06-19)
Anti-Galα1,3Galβ-R natural antibodies are responsible for hyperacute rejection in pig-to-primate xenotransplantation. Although the generation of pigs lacking the α1,3galactosyltransferase (GalT) has overcome hyperacute rejection, antibody-mediated rejection is still a problem. It is possible that other enzymes synthesize antigens similar to
Delayed urticaria to beef ingestion.
Henry Benjamin Coker et al.
Journal of the American Academy of Dermatology, 68(3), e101-e101 (2013-02-12)
T Biedermann et al.
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 63 Suppl 1, 76-79 (2012-05-11)
Delayed immediate-type allergy to innards and red meat can be mediated by IgE antibodies to galactose-α-1, 3-galactose (α-Gal). Apart from humans and Old World apes, α-Gal is ubiquitously expressed in glycoproteins and glycolipids. Thus, as α-Gal is immunogenic for humans
Delayed mammalian meat-induced anaphylaxis due to galactose-α-1,3-galactose in 5 European patients.
Ramón Nuñez et al.
The Journal of allergy and clinical immunology, 128(5), 1122-1124 (2011-08-13)
Jens Magnus Bernth-Jensen et al.
Journal of immunological methods, 373(1-2), 26-35 (2011-08-13)
As much as one percent of antibodies in human plasma are reported to be specific for the non-human disaccharide structure αGal. Various microbes express αGal. However, the implications of anti-αGal antibodies for the anti-microbial defenses are poorly established. With the
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