G7903
Glycophorin Predominantly glycophorin A from blood type MM
lyophilized powder
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About This Item
Form:
lyophilized powder
Biological source:
human blood (type MN)
biological source
human blood (type MN)
form
lyophilized powder
concentration
20-40% (Lowry)
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... GYPA(2993)
General description
Glycophorin A (GpA) is an important sialoglycoprotein on human red cells. It is one of the best characterized mammalian integral membrane proteins, containing three distinct domains. A large hydrophilic portion carries the NH2-terminal and is positioned on the external surface of the red cell, and the COOH-terminal is found in the cytoplasm. A hydrophobic segment of 23 amino acids (embedded within the lipid bilayer ) connects these two hydrophilic sequences.
Application
Glycophorin A was used to study the Plasmodium falciparum erythrocyte-binding antigen-175 (EBA175)-glycophorin-A interaction.
Biochem/physiol Actions
A membrane glycoprotein with several isoforms that interact with other membrane proteins to confer shape and antigenicity to erythrocytes.
It is a membrane glycoprotein with several isoforms that interact with other membrane proteins to confer shape and antigenicity to erythrocytes.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Glycophorin A as an erythroid marker in normal and malignant hematopoiesis.
L C Andersson et al.
Haematology and blood transfusion, 26, 338-344 (1981-01-01)
Bishwanath Kumar Chourasia et al.
Infection and immunity, 88(2) (2019-11-13)
Cytoadherence-linked asexual gene 9 (Clag9), a conserved Plasmodium protein expressed during the asexual blood stages, is involved in the cytoadherence of infected red blood cells (RBCs) to the endothelial lining of blood vessels. Here, we show that Plasmodium falciparum Clag9
Global Trade Item Number
| SKU | GTIN |
|---|---|
| G7903-1MG | 04061826738689 |
| G7903-.5MG | 04061833643594 |