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Merck
CN

G8031

Sigma-Aldrich

Glycopeptidase F from Elizabethkingia meningoseptica

buffered aqueous glycerol solution

Synonym(s):

N-Glycosidase F, PNGase F, Peptide N-glycosidase

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About This Item

CAS Number:
EC Number:
UNSPSC Code:
12352204
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form

buffered aqueous glycerol solution

shipped in

dry ice

storage temp.

−20°C

Application

Used to deglycosylate protein.

Physical form

Solution in 50% glycerol containing 100 mM sodium phosphate, 25 mM EDTA and 5 mM sodium azide, pH 7.2

Other Notes

1 unit is the enzyme activity which hydrolyzes 1 nmole dabsyl fibrin glycopeptide within 1 minute at 37°C and pH 7.8.

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Hui Zhou et al.
Analytical biochemistry, 427(1), 33-35 (2012-04-21)
Common de-N-glycosylation protocols usually require a lengthy incubation time. Although pressure cycling technology or scientific microwave reactors can accelerate this enzyme reaction, they may not be easily accessible. In this brief report, we employed an alternative strategy using a standard
Helle Malerod et al.
Journal of proteome research, 12(1), 248-259 (2012-12-05)
The adenocarcinoma cell line HeLa serves as a model system for cancer research in general and cervical cancer in particular. In this study, hydrazide enrichment in combination with state-of-the art nanoLC-MS/MS analysis was used to profile N-linked glycosites in HeLa
Yukiko Kamiya et al.
FEBS letters, 586(8), 1141-1146 (2012-05-12)
PUB domains are identified in several proteins functioning in the ubiquitin (Ub)-proteasome system and considered as p97-binding modules. To address the further functional roles of these domains, we herein characterized the interactions of the PUB domain of peptide:N-glycanase (PNGase) with
Anuradha Gosain et al.
BMC biochemistry, 13, 9-9 (2012-06-12)
Peptide: N- glycanase (PNGase) enzyme cleaves oligosaccharides from the misfolded glycoproteins and prepares them for degradation. This enzyme plays a role in the endoplasmic reticulum associated degradation (ERAD) pathway in yeast and mice but its biological importance and role in
Yuki Masahara-Negishi et al.
Biochimica et biophysica acta, 1820(10), 1457-1462 (2012-06-05)
The cytoplasmic peptide:N-glycanase (PNGase) is a deglycosylating enzyme involved in the ER-associated degradation (ERAD) process, while ERAD-independent activities are also reported. Previous biochemical analyses indicated that the cytoplasmic PNGase orthologue in Arabidopsis thaliana (AtPNG1) can function as not only PNGase

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