G8040
γ-Glutamyltranspeptidase from bovine kidney
Type I, 2.0-10 unit/mg solid
Synonym(s):
γ-GT, γ-Glutamyltransferase, (5-Glutamyl)peptide:amino-acid 5-glutamyltransferase, GGTP
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About This Item
CAS Number:
UNSPSC Code:
12352204
EC Number:
232-931-5
MDL number:
type
Type I
specific activity
2.0-10 unit/mg solid
storage temp.
−20°C
Analysis Note
Crude
Other Notes
One unit will liberate 1.0 μmole of p-nitroaniline from L-γ-glutamyl-p-nitroanilide per min at pH 8.5 at 25°C.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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γ-Glutamyl transferase and its role as a biomarker of systemic malignancies other than hepatocellular carcinomas.
Shailendra Kapoor
European journal of gastroenterology & hepatology, 25(3), 387-387 (2013-01-26)
Stephanie Wickham et al.
The Biochemical journal, 450(3), 547-557 (2013-01-11)
GGT (γ-glutamyl transpeptidase) is an essential enzyme for maintaining cysteine homoeostasis, leukotriene synthesis, metabolism of glutathione conjugates and catabolism of extracellular glutathione. Overexpression of GGT has been implicated in many pathologies, and clinical inhibitors of GGT are under development for
R Foddis et al.
Giornale italiano di medicina del lavoro ed ergonomia, 34(3 Suppl), 565-567 (2013-02-15)
The GGT enzyme, considered for years only as a marker of liver disease and alcohol abuse, has now revealed a risk of death for many causes. Through a molecular exclusion chromatography on FPLC system (Fast Protein Liquid Chromatography), it is
Mathias Oertli et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(8), 3047-3052 (2013-02-06)
Infection with the gastric bacterial pathogen Helicobacter pylori is typically contracted in early childhood and often persists for decades. The immunomodulatory properties of H. pylori that allow it to colonize humans persistently are believed to also account for H. pylori's
BK virus-associated progressive multifocal leukoencephalopathy.
Kathryn L Daveson et al.
The Medical journal of Australia, 198(4), 216-218 (2013-03-05)
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