G8165
Galanin (1-13)-Neuropeptide Y (25-36) Amide
≥90%
Synonym(s):
m32
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C136H209N41O34
Molecular Weight:
2962.37
UNSPSC Code:
12352200
MDL number:
Biochem/physiol Actions
This chimeric peptide is a high affinity galanin receptor antagonist (IC50=0.1 nM in rat hypothalamus membranes and Kd=0.01 nm in rat spinal cord membranes). This peptide is also recognized by neuropeptide Y receptors (IC50=0.25 μM in rat cerebral cortex membranes) and is a Y2 agonist in rat vas deferens.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
K Arvidsson et al.
Biochemistry, 32(30), 7787-7798 (1993-08-03)
The 25 amino acid residue chimeric peptide M32, galanin(1-13)-neuropeptide Y(25-36)-amide, was synthesized. The peptide was found to be recognized by both galanin and NPY receptors. The solution structure in 30% (v/v) 1,1,1,3,3,3-hexafluoro-2-propanol was examined by 2-D 1H-NMR and by CD.
U Kahl et al.
British journal of pharmacology, 111(4), 1129-1134 (1994-04-01)
1. The effects and binding characteristics of a series of chimeric galanin-neuropeptide Y (NPY) peptides were examined in various preparations known to contain a predominant population of either Y1 or Y2 receptors for NPY or galanin receptors. 2. NPY suppressed
X J Xu et al.
British journal of pharmacology, 116(3), 2076-2080 (1995-10-01)
1. The role of endogenous galanin in somatosensory processing has been studied with galanin receptor antagonists. The new galanin receptor ligands C7, M32, M38 and M40 bind with high affinity (Kd in nanomolar range) to spinal cord galanin receptors and
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service