G8887
Glucokinase from Bacillus stearothermophilus
lyophilized powder, ≥250 units/mg protein
Synonym(s):
ATP:D-glucose-6-phosphotransferase
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About This Item
Specific activity:
≥250 units/mg protein
Biological source:
Bacillus sp. (B. stearothermophilus)
biological source
Bacillus sp. (B. stearothermophilus)
form
lyophilized powder
specific activity
≥250 units/mg protein
composition
Protein, ≥60% biuret
shipped in
dry ice
storage temp.
−20°C
Quality Level
Physical form
Lyophilized powder containing Tris buffer salts
Other Notes
One unit will phosphorylate 1.0 μmole of D-glucose to D-glucose 6-phosphate per min at pH 9.0 at 30 °C.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Päivi J Miettinen et al.
Duodecim; laaketieteellinen aikakauskirja, 128(19), 1989-1998 (2012-11-20)
MODY (Maturity-Onset Diabetes of the Young) is a group of monogenic disorders characterized by autosomally dominantly inherited diabetes or hyperglycemia typically detected during adolescence or young adulthood. Usually there is at least one person in the family having developed the
Comment on: Chakera et al. Antenatal diagnosis of fetal genotype determines if maternal hyperglycemia due to a glucokinase mutation requires treatment. Diabetes Care 2012;35:1832-1834.
Edoardo Tartaglia et al.
Diabetes care, 36(1), e14-e14 (2012-12-25)
Response to Comment on: Chakera et al. Antenatal diagnosis of fetal genotype determines if maternal hyperglycemia due to a glucokinase mutation requires treatment. Diabetes Care 2012;35:1832-1834.
Ali J Chakera et al.
Diabetes care, 36(1), e15-e15 (2012-12-25)
Matthew D Blankschien et al.
ACS nano, 7(1), 654-663 (2012-12-15)
The use of plasmonic nanoparticle complexes for biomedical applications such as imaging, gene therapy, and cancer treatment is a rapidly emerging field expected to significantly improve conventional medical practices. In contrast, the use of these types of nanoparticles to noninvasively
Lei Zhang et al.
European journal of medicinal chemistry, 58, 624-639 (2012-11-28)
Dual-target-directed agents simultaneously inhibiting glycogen phosphorylase (GP) and activating glucokinase (GK) could decelerate the inflow of glucose from glycogenolysis and accelerate the outflow of glucose in the liver, therefore allow for a better control over hyperglycaemia in a synergetic manner.
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