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Merck
CN

G9541

Sigma-Aldrich

G Protein Antagonist

≥90% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C57H64N12O9S
CAS Number:
Molecular Weight:
1093.26
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.32
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Assay

≥90% (HPLC)

storage temp.

−20°C

Gene Information

human ... CHRM2(1129)

Amino Acid Sequence

Glp-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2

Biochem/physiol Actions

Inhibits the activation of Gαi or Gαo by M2 muscarinic cholinergic receptor.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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H Mukai et al.
The Journal of biological chemistry, 267(23), 16237-16243 (1992-08-15)
A substance P (SP) analog, [D-Pro4,D-Trp7,9,10] SP4-11, is known to inhibit the actions of various structurally unrelated messenger molecules as well as SP. Our studies on the effects of this peptide on the regulation of purified G proteins by receptor

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