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Merck
CN

GW10762

Anti-SMS antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-MRSR, Anti-Spermine synthase

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2

Key Documents

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biological source

chicken

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, human, mouse

manufacturer/tradename

Genway 15-288-10762

technique(s)

western blot: suitable

NCBI accession no.

NP_004586.1

UniProt accession no.

P52788

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

200

Gene Information

human ... SMS(6611)

Immunogen

Immunogen Sequence: GI # 4759152, sequence 206-335
Recombinant spermine synthase; SpS

Application

Anti-SMS antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200.

Biochem/physiol Actions

SMS (spermine synthase) encodes a member of the spermidine/spermin synthase family. It catalyzes the synthesis of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM). Defects in this gene are linked to X-linked Snyder-Robinson mental retardation syndrome.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
039K2193
029K2290

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Partial purification and characterization of spermine synthase from rat brain.
P Hannonen et al.
Biochimica et biophysica acta, 289(1), 225-231 (1972-11-10)
A Lauren Cason et al.
European journal of human genetics : EJHG, 11(12), 937-944 (2003-09-26)
Polyamines (putrescine, spermidine, spermine) are ubiquitous, simple molecules that interact with a variety of other molecules in the cell, including nucleic acids, phospholipids and proteins. Various studies indicate that polyamines are essential for normal cell growth and differentiation. Furthermore, these

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