Skip to Content
Merck
CN

GW10842F

Anti-Rev antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-ART/TRS, Anti-Anti-Repression transactivator protein, Anti-Protein Rev

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00212000
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

chicken

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

viral

manufacturer/tradename

Genway 15-288-10842F

technique(s)

western blot: suitable

NCBI accession no.

AAK08487.1

UniProt accession no.

P04618

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human immunodeficiency virus 1 ... Rev(155908)

General description

Rev is a regulatory protein of human immunodeficiency virus type 1. It consists of a hydrophobic core, which is formed by binding to another REV molecule and arginine-rich motifs (ARMs).

Immunogen

Immunogen Sequence: GI # 12831140, sequence 1-116
Recombinant Rev protein (HIV-1 vector pNL4-3)

Application

Anti-Rev antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200.

Biochem/physiol Actions

Rev is involved in the stabilization and transport of the viral mRNA. It is involved in the up-regulation of the gag- and env-producing mRNAs via cis-acting element in the env region of HIV-1, named rev responsive element. It increases the stability of the unspliced viral mRNA and promotes the transport of the viral mRNA having the rev-responsive element from the nucleus to the cytoplasm.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
039K1755
029K1671
029K1673
029K1672

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Xianyang Fang et al.
Cell, 155(3), 594-605 (2013-11-19)
Nuclear export of unspliced and singly spliced viral mRNA is a critical step in the HIV life cycle. The structural basis by which the virus selects its own mRNA among more abundant host cellular RNAs for export has been a
B K Felber et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(5), 1495-1499 (1989-03-01)
rev (trs/art) is an essential human immunodeficiency virus type 1 (HIV-1) regulatory protein. rev increases the levels of the gag- and env-producing mRNAs via a cis-acting element in the env region of HIV-1, named rev-responsive element. Our results show that

Related Content

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service