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Key Documents

GW21015

Sigma-Aldrich

Anti-HRAS antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-GTPase HRas, Anti-K-ras, Anti-N-ras, Anti-Transforming protein p21, Anti-V-Ha-ras Harvey rat sarcoma viral oncogene homolog isofrom 1, Anti-c-H-ras, Anti-p21ras

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

chicken

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, rat

manufacturer/tradename

Genway 15-288-21015

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HRAS(3265)

Immunogen

Immunogen Sequence: GI # 4885425, sequence 116-189
Recombinant V-Ha-ras Harvey rat sarcoma viral oncogene homolog isofrom 1

Application

Anti-HRAS antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

GTPase HRas is an enzyme encoded by the HRAS gene in humans. It is located on the short (p) arm of chromosome 11 at position 15.5. Somatic mutation of this gene is restricted to a specific proportion of sporadic pheochromocytoma (PCC). It is strictly monomeric at comparable densities in solution and dimerization is a general property of native H-Ras on membrane surfaces. Missense mutation in the HRAS gene causes an autosomal-dominant syndrome, Costello syndrome.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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