Anti-c-Myc Tag Antibody

Immunogen Sequence: GI # 12962935, sequence 410-419

Synthetic peptide of V-myc myelocytomatosis viral oncogene homolog.

Anti-c-Myc (ab1) antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Myc (c-Myc) is a regulatory gene and encodes for a transcription factor. It is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. Myc is associated with aggressive behaviour in several cancers. c-MYC gain with lung adenocarcinoma is a candidate for additional first-line treatment to mitigate increased risk for disease progression and death. It plays an important role in the pathogenesis of B-cell prolymphocytic leukemia (B-PLL).

Solution in phosphate buffered saline containing 0.02% sodium azide.

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