GW21187
Anti-E2F2 antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-Transcription factor E2F2
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About This Item
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, mouse
manufacturer/tradename
Genway 15-288-21187
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... E2F2(1870)
Application
Anti-E2F2 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Transcription factor E2F2 is a protein encoded by the E2F2 gene in humans. It is associated with the regulation of cell-cycle and blood pressure. E2F2 is a transcription factor that helps regulate the expression of a number of genes that are important in cell proliferation. The cell cycle progression is dependent on the transcriptional activity of E2F2 and are associated with pocket proteins that binds to DNA as a heterodimer of two distinct proteins. E2F-2 is functionally and immunologically associated with one of these two distinct proteins.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
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Instructions
R Halaban et al.
The Journal of experimental medicine, 191(6), 1005-1016 (2000-03-23)
Inactivation of the retinoblastoma tumor suppressor protein (pRb) has been implicated in melanoma cells, but the molecular basis for this phenotype has not yet been elucidated, and the status of additional family members (p107 and p130, together termed pocket proteins)
Heiko Funke-Kaiser et al.
Human molecular genetics, 12(4), 423-433 (2003-02-05)
The endothelin-converting enzyme (ECE)-1 gene is a candidate for human blood pressure (BP) regulation and we report the identification of the new gene variants T-839G, C-338A, L75F, A677V and C+295T. Transient transfection of the reporter constructs containing the -338A allele
J A Lees et al.
Molecular and cellular biology, 13(12), 7813-7825 (1993-12-01)
E2F is a transcription factor that helps regulate the expression of a number of genes that are important in cell proliferation. Recently, several laboratories have isolated a cDNA clone that encodes an E2F-like protein, known as E2F-1. Subsequent characterization of