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GW21429

Sigma-Aldrich

Anti-ADAM23 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-A disintegrin and metalloproteinase domain 23

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

chicken

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

manufacturer/tradename

Genway 15-288-21429

technique(s)

western blot: suitable

NCBI accession no.

NP_003803.1

UniProt accession no.

O75077

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ADAM23(8745)

Related Categories

Immunogen

Immunogen Sequence: GI # 4501913, sequence 72-144
Recombinant ADAM metallopeptidase domain 23 preproprotein

Application

Anti-ADAM23 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Disintegrin and metalloproteinase domain-containing protein 23 is an enzyme encoded by the ADAM23 gene in humans and is a member of a disintegrin and metalloprotease (ADAM) family. It is higly expressed in the brain and may function as integrin ligands in the brain along with other proteins. ADAM23 is associated with the progression of non-small-cell lung carcinoma (NSCLC) and its downregulation may be correlated with promoter methylation. It may be down-regulated by aberrant promoter hypermethylation during the progression of colorectal cancer. ADAM23 is down-regulated by methylation in brain tumors, which is a rare event.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
029K1814

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