GW22329A
Anti-CSTF1 (ab1) antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
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About This Item
UNSPSC Code:
12352203
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
rat, mouse, human
manufacturer/tradename
Genway 15-288-22329A
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CSTF1(1477)
Immunogen
Immunogen Sequence: GI # 4557491, sequence 1-200
Recombinant cleavage stimulation factor subunit 1
Application
Anti-CSTF1 (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Cleavage stimulation factor (50kDa subunit) is a protein encoded by the CSTF1 gene in humans. It has a link between transcription-coupled RNA processing and DNA repair and has a role in this response. CSTF1 participates in the regulation of endogenous transcripts under DNA-damaging conditions. Transducin repeats has a possible role in specifically CstF function and in other β-subunit homologues.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
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Murat A Cevher et al.
The EMBO journal, 29(10), 1674-1687 (2010-04-10)
We previously showed that mRNA 3' end cleavage reaction in cell extracts is strongly but transiently inhibited under DNA-damaging conditions. The cleavage stimulation factor-50 (CstF-50) has a role in this response, providing a link between transcription-coupled RNA processing and DNA
Y Takagaki et al.
The Journal of biological chemistry, 267(33), 23471-23474 (1992-11-25)
Cleavage stimulation factor (CstF) is one of the multiple factors required for polyadenylation of mammalian pre-mRNAs in vitro. We have shown previously that this factor is composed of three distinct subunits of 77, 64, and 50 kDa, and that the