GW22383A
Anti-PNLIPRP2 antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, rat, mouse
manufacturer/tradename
Genway 15-288-22383A
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... PNLIPRP2(5408)
Immunogen
Immunogen Sequence: GI # 4885555, sequence 16-139
Recombinant pancreatic lipase-related protein 2
Application
Anti-PNLIPRP2 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
PNLIPRP2 (pancreatic lipase-related protein 2) is also know as PLRP2 . It can digest fats in human milk and formula. In mice, it is essential for fat digestion, and in humans, its role in fat digestion is unclear. IL-4 induces PLRP2 in cytotoxic T lymphocytes (CTLs). PLRP2 can help in killing tumor cells and is alone required for lipid-dependent cytotoxicity mediated by cytotoxic T lymphocytes (CTLs).
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
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Karin Johnson et al.
Pediatric research, 74(2), 127-132 (2013-06-05)
Dietary fats must be digested into fatty acids and monoacylglycerols prior to absorption. In adults, colipase-dependent pancreatic triglyceride lipase (PTL) contributes significantly to fat digestion. In newborn rodents and humans, the pancreas expresses low levels of PTL. In rodents, a
Bryce N Alves et al.
Cell biochemistry and function, 27(5), 296-308 (2009-06-24)
IL-4 induces a lipase, pancreatic lipase related protein 2 (PLRP2), in cytotoxic T lymphocytes (CTLs). Because PLRP2 in semen can mediate lipid-dependent toxicity to sperm, we questioned whether CTL-derived PLRP2 could support similar cytotoxicity toward tumor cells. Recombinant PLRP2 was
Xunjun Xiao et al.
The Journal of biological chemistry, 286(30), 26353-26363 (2011-06-10)
In newborn mice, PLRP2 is essential for fat digestion. In human infants, the role of PLRP2 in fat digestion is unclear, as it has poor activity against long-chain triglycerides in vitro. Also, many infants carry a genetic polymorphism resulting in
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Instructions
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