GW22661
Anti-DNMT3A2 antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
rat, human, mouse
manufacturer/tradename
Genway 15-288-22661
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... DNMT3A(1788)
General description
Chicken polyclonal anti-DNMT3A2 antibody reacts with human, rat, and mouse DNA (cytosine-5-)-methyltransferase 3 α 2 methyltransferases.
DNA (cytosine-5-)-methyltransferase 3 α (DNMT3A2) is involved in the epigenetic modification of genes involved in processes that regulate embryonic development, imprinting, and X-chromosome inactivation. For instance DNMT3A promotes the down regulation of Oct-3/4 to prevent reprogramming during early cell differentiation from the pluripotent state. Dysfunctional DNMT3A have been associated with incidence of acute myeloid leukemia (AML).
Immunogen
Immunogen Sequence: GI # 28559069, sequence 1-300
Recombinant DNA cytosine methyltransferase 3 α isoform a
Application
Chicken polyclonal anti-DNMT3A2 antibody is used to tag DNA (cytosine-5-)-methyltransferase 3 α 2 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of DNA (cytosine-5-)-methyltransferase 3 α 2 in post-translational (epigenetic) gene regulation involving the processes of embryonic development, imprinting, and X-chromosome inactivation.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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