Anti-RGS8 antibody produced in chicken

Immunogen Sequence: GI # 16117777, sequence 1-85

Recombinant regulator of G-protein signalling 8

Anti-RGS8 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Regulator of G-protein signaling 8 is a protein encoded by the RGS8 gene in humans. It is a neuron-specific regulator of G-protein signaling (RGS) protein that belongs to the B/R4 subfamily. RGS8 is recruited to the plasma membrane where G-proteins are activated mainly by direct association with Gα. It regulates G-protein signaling protein induced in neuronally differentiated P19 cells. RGS proteins help in modulating signaling through heterotrimeric G-proteins. It acts to enhance the intrinsic GTPase activity of the Gα subunit. RGS protein is found to enhance the "kinetic efficacy" of the ternary complex by direct association with the G-protein α subunit. RGS8 expression is improved upon the ′kinetic efficacy′ of G-protein activation.

Solution in phosphate buffered saline containing 0.02% sodium azide.

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