GW22898
Anti-RGS17 antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-Regulator of G-protein signaling 17
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, human, rat
manufacturer/tradename
Genway 15-288-22898
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... RGS17(26575)
Immunogen
Immunogen Sequence: GI # 21361405, sequence 41-100
Recombinant regulator of G-protein signalling 17
Application
Anti-RGS17 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Regulator of G-protein signaling 17 is a protein encoded by the RGS17 gene in humans and is mapped to chromosome 6q23-25. RGS17 encodes a member of the regulator of G-protein signaling RGS-Rz subfamily. It is differentially expressed in hepatocellular carcinoma (HCC) and plays a central role in regulating transformed hepatocyte tumorgenicity. RGS17 is over-expressed in human lung adenocarcinomas and plays an important role in lung tumor growth.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Eugene Sokolov et al.
Cellular signalling, 23(10), 1603-1610 (2011-05-31)
Guanine nucleotide regulatory proteins (G-proteins) are central to normal hepatocyte function and are implicated in hepatic disease initiation and progression. Regulators of G-protein signaling (RGS) are critical to defining G-protein-dependent signal fidelity, yet the role of RGS proteins in the
Ming You et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(8), 2666-2674 (2009-04-09)
We have previously mapped a major susceptibility locus influencing familial lung cancer risk to chromosome 6q23-25. However, the causal gene at this locus remains undetermined. In this study, we further refined this locus to identify a single candidate gene, by
Huiping Zhang et al.
Behavioral and brain functions : BBF, 8, 23-23 (2012-05-18)
RGS17 and RGS20 encode two members of the regulator of G-protein signaling RGS-Rz subfamily. Variation in these genes may alter their transcription and thereby influence the function of G protein-coupled receptors, including opioid receptors, and modify risk for substance dependence.
Yihua Sun et al.
Biochemical and biophysical research communications, 396(2), 501-507 (2010-04-28)
Lung cancer is one of the most devastating diseases worldwide. RGS17 is previously shown to be over-expressed in human lung adenocarcinomas and plays an important role in lung tumor growth. Here we have identified a miRNA, has-mir-182, involved in the
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