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Merck
CN

GW22901

Anti-RGS9 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Regulator of G-protein signaling 9

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
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biological source

chicken

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human, rat

manufacturer/tradename

Genway 15-288-22901

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... RGS9(8787)

Immunogen

Immunogen Sequence: GI # 4506521, sequence 21-200
Recombinant regulator of G-protein signalling 9

Application

Anti-RGS9 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem/physiol Actions

Regulator of G-protein signalling 9 is a human gene encoding for a protein that is involved in regulation of signal transduction inside cells. The protein belongs to RGS family of GTPase accelerating proteins. It is expressed specifically in the striatum, a brain region involved in controlling movement, motivation, mood and addiction. RGS9-1 regulates phototransduction in rods and cones and RGS9-2 regulates dopamine and opioid signaling in the basal ganglia. RGS9 plays an essential role at intracellular compartment and its functioning.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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Jeremy Celver et al.
Journal of neurochemistry, 114(3), 739-749 (2010-05-19)
Regulator of G protein signaling 9-2 (RGS9-2), a member of the RGS family of GTPase accelerating proteins, is expressed specifically in the striatum, a brain region involved in controlling movement, motivation, mood and addiction. RGS9-2 can be found co-localized with
Mei Tian et al.
PloS one, 8(3), e58832-e58832 (2013-04-05)
The transducin GTPase-accelerating protein complex, which determines the photoresponse duration of photoreceptors, is composed of RGS9-1, Gβ5L and R9AP. Here we report that RGS9-1 and Gβ5L change their distribution in rods during light/dark adaptation. Upon prolonged dark adaptation, RGS9-1 and
Kirill A Martemyanov et al.
Progress in molecular biology and translational science, 86, 205-227 (2009-01-01)
Two splice isoforms of the ninth member of the regulator of G protein signaling (RGS) protein family are expressed in the nervous system, where they are engaged in such diverse functions as vision and behavior. RGS9-1 regulates phototransduction in rods