H0285
HIV-1 nef
>95% (SDS-PAGE), recombinant, expressed in E. coli, Galactosidase-tagged
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About This Item
UNSPSC Code:
12352200
MDL number:
recombinant
expressed in E. coli
assay
>95% (SDS-PAGE)
mol wt
20 kDa (plus 114 kDa β-Gal tag)
UniProt accession no.
storage temp.
−20°C
Gene Information
human immunodeficiency virus 1 ... nef(156110)
General description
Contains amino acid residues [3-190] of HIV-1 nef antigen.
Biochem/physiol Actions
Positive control for HIV antibodies.
Physical form
Solution in 8 M urea; 20 mM Tris-HCL, ph 8.0; 10 mM β−mercaptoethanol.
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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J Lama et al.
Journal of virology, 74(20), 9396-9402 (2000-09-23)
Human immunodeficiency virus (HIV) Nef downregulates the antigen recognition molecules major histocompatibility complex class I and CD4. Downregulation of surface CD4 by Nef relies on the ability of this viral protein to redirect the endocytic machinery to CD4. However, by
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