H0411
Hepatocyte Growth Factor Receptor (c-Met)/Fc Chimera from mouse
>95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder
Synonym(s):
HGF Receptor (c-Met)
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About This Item
UNSPSC Code:
51111800
MDL number:
biological source
mouse
recombinant
expressed in baculovirus infected Sf21 cells
assay
>95% (SDS-PAGE)
form
lyophilized powder
mol wt
calculated mol wt 128 kDa
storage condition
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Met(17295)
Biochem/physiol Actions
Heterodimeric transmembrane glycoprotein with binding capacity for c-Met. Activation of this receptor has been correlated with induction of the Ras pathway.
Physical form
Lyophilized from 0.2 μm filtered solution in phosphate buffered saline.
Analysis Note
The biological activity is measured by its ability to bind human HGF.
Other Notes
Extracellular domain fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Cornoglio, P.M. et al.
Guidebook to Cytokines and Their Receptors, 185-185 (1994)
A M Chan et al.
Oncogene, 2(6), 593-599 (1988-06-01)
The DNA sequence of cDNA clones prepared from transcripts of the mouse met proto-oncogene reveals that the mouse met gene encodes a 1380 amino acid protein with the characteristics of a growth factor receptor. This protein can be divided into
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