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H0791

Anti-HOXA10 (C-terminal) antibody produced in rabbit

Name: Anti-HOXA10 (C-terminal) antibody produced in rabbit
Brand: SIGMA

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-HOX-1.8, Anti-HOX1H, Anti-Homeobox 1H, Anti-Homeobox A10

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~50 kDa

species reactivity

human

technique(s)

western blot: 1:500-1:1,000 using lysate of HEK-293T cells over expressing human HOXA10

UniProt accession no.

P31260

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HOXA10(3206)

General description

Homeobox A10 (HOXA10) belongs to the HOX transcription factor family. HOX transcription factors are classified as four clusters, such as cluster A, B, C and D. HOXA10 is localized in A cluster on chromosome 7.

Application

Anti-HOXA10 (C-terminal) antibody produced in rabbit has been used in immunoblotting.

Biochem/physiol Actions

Homeobox A10 (HOXA10) is highly essential for the growth of erythroid and megakaryocytic lineages. The expression of HOXA10 was found to be altered in endometriosis. It also participates in gene expression, morphogenesis and differentiation. HOXA10 plays a key role in gastric cancer, oral squamous cell carcinoma, prostate carcinoma, ovarian clear cell adenocarcinoma, endometrial adenocarcinoma.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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nwg

Storage Class

12 - Non Combustible Liquids

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

059K4779

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LncHOXA10 drives liver TICs self-renewal and tumorigenesis via HOXA10 transcription activation

Shao M, et al.

Molecular Cancer, 17 (2018)

HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development

Magnusson M, et al.

Blood, 109(9), 3687-3696 (2007)

Global Trade Item Number

SKU	GTIN
H0791-25UL	04061837771804
H0791-200UL	04061835678211

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