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Merck
CN

H2538

Sigma-Aldrich

Anti-Hamartin antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
MFCD06201936
UNSPSC Code:
12352203

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 130-150 kDa

species reactivity

mouse, human, rat

technique(s)

western blot: 0.25-0.5 μg/mL using extracts of rat brain and mouse NIH3T3 cells
western blot: 0.5-1.0 μg/mL using whole extract of human HeLa cells

UniProt accession no.

Q92574

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... TSC1(7248)
mouse ... Tsc1(64930)
rat ... Tsc1(60445)

Immunogen

synthetic peptide corresponding to amino acid residues 1152-1164 of human hamartin with N-terminal added Cys-Gly-Gly chain, conjugated to KLH. The corresponding sequence is identical in rat and differs by one amino acid in mouse.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
123K4858

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Shalmali Avinash Pradhan et al.
Nucleic acids research, 42(10), 6243-6255 (2014-04-22)
The TSC2 gene, mutated in patients with tuberous sclerosis complex (TSC), encodes a 200 kDa protein TSC2 (tuberin). The importance of TSC2 in the regulation of cell growth and proliferation is irrefutable. TSC2 in complex with TSC1 negatively regulates the

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