H2644
1-O-Palmityl-2-O-methyl-rac-glycerol
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About This Item
Empirical Formula (Hill Notation):
C20H42O3
CAS Number:
Molecular Weight:
330.55
UNSPSC Code:
12352200
MDL number:
SMILES string
CCCCCCCCCCCCCCCCOCC(CO)OC
storage temp.
−20°C
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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N Grosman
Immunopharmacology, 20(2), 143-149 (1990-09-01)
We have previously shown that the ether lipid AMG (1-O-hexadecyl-2-O-methyl-sn-glycerol) has both synergistic and inhibitory effects on mast cell responses to the ionophore A23187. The present investigation showed only inhibitory effects of AMG in antigen- and compound 48/80-induced histamine release.
J A Pinxteren et al.
The Biochemical journal, 356(Pt 1), 287-296 (2001-05-05)
Mast cells permeabilized by streptolysin O undergo exocytosis when stimulated with Ca(2+) and guanosine 5'-[gamma-thio]triphosphate but become progressively refractory to this stimulus if it is delayed. This run-down of responsiveness occurs over a period of 20-30 min, during which the
N Grosman
Immunopharmacology, 22(1), 39-47 (1991-07-01)
The ether lipid AMG (1-O-hexadecyl-2-O-methylglycerol) has previously been shown to have both enhancing and inhibitory effects on histamine release from isolated rat mast cells. In addition, a synergistic interaction with the phorbol ester TPA indicated protein kinase C activation. In
T Syrovets et al.
Blood, 89(12), 4574-4583 (1997-06-15)
We have previously reported that the serine protease plasmin generated during contact activation of human plasma triggers biosynthesis of leukotrienes (LTs) in human peripheral monocytes (PMs), but not in polymorphonuclear neutrophils (PMNs). We now show that purified plasmin acts as
K F Rabe et al.
Fundamental & clinical pharmacology, 6(8-9), 353-358 (1992-01-01)
Leukotriene B4 (LTB4) and the protein kinase C activator, 4-beta-phorbol dibutyrate (PDBu), both induced a pronounced and concentration-dependent stimulation of hydrogen peroxide (H2O2) generation by purified guinea pig peritoneal eosinophils in the concentration range 1 nM-1 microM. The LTB4 response
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