H3021
Antiflammin-2
≥97% (HPLC)
Synonym(s):
Anti-inflammatory peptide 2, His-Asp-Met-Asn-Lys-Val-Leu-Asp-Leu
Sign Into View Organizational & Contract Pricing
About This Item
Empirical Formula (Hill Notation):
C46H77N13O15S
CAS Number:
Molecular Weight:
1084.25
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
≥97% (HPLC)
composition
Peptide content, ~65%
storage temp.
−20°C
SMILES string
CSCCC(NC(=O)C(CC(O)=O)NC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(CC(C)C)C(O)=O
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
新产品
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Wayne B Anderson et al.
Chemical research in toxicology, 17(5), 650-662 (2004-05-18)
Dichloroacetic acid (DCA) is a drinking water contaminant, a therapeutic agent, and a rodent carcinogen. Glutathione transferase zeta (GSTZ1-1) catalyzes the biotransformation of a range of alpha-haloalkanoates and the cis-trans isomerization of maleylacetoacetate. GSTZ1-1 catalyzes the bioactivation of fluorine-lacking dihaloacetates
Degradation of antiflammin 2 in aqueous solution.
J L Wolfe et al.
Journal of pharmaceutical sciences, 83(12), 1762-1764 (1994-12-01)
J M Ye et al.
Journal of pharmaceutical sciences, 85(7), 695-699 (1996-07-01)
Antiflammin 2 (HDMNKVLDL, AF2) is a synthetic peptide derived from the region of highest sequence similarity of lipocortin I and uteroglobin, and is a potent antiinflammatory agent without any known side effects of corticosteroids. The antiinflammatory activity of AF2 has
Ahmad M Kamal et al.
TheScientificWorldJournal, 6, 1375-1384 (2006-10-31)
The anti-inflammatory actions of the nonapeptide antiflammin-2, identified by homology with uteroglobin and annexin-A1 sequences, have been described in some detail, yet its mechanisms of action remain elusive. Since recent data indicate an involvement of the formyl peptide receptor (FPR)-like
K E Rodgers et al.
Journal of investigative surgery : the official journal of the Academy of Surgical Research, 10(1-2), 31-36 (1997-01-01)
Adhesion formation is a major source of postoperative morbidity and mortality. Therefore, the reduction of postoperative adhesion formation would be of clinical benefit. Various modalities have been shown to reduce adhesion formation, including fibrinolytic enzymes, nonsteroidal anti-inflammatory drugs, and barriers
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service