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Merck
CN

H4155

Sigma-Aldrich

7-Hydroxyflavanone

Synonym(s):

7-Hydroxy-2-phenylchroman-4-one

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About This Item

Empirical Formula (Hill Notation):
C15H12O3
CAS Number:
Molecular Weight:
240.25
MDL number:
UNSPSC Code:
12352100
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mp

188-190 °C (lit.)

SMILES string

Oc1ccc2C(=O)CC(Oc2c1)c3ccccc3

InChI

1S/C15H12O3/c16-11-6-7-12-13(17)9-14(18-15(12)8-11)10-4-2-1-3-5-10/h1-8,14,16H,9H2

InChI key

SWAJPHCXKPCPQZ-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Přemysl Mladěnka et al.
Journal of inorganic biochemistry, 105(5), 693-701 (2011-04-01)
Flavonoids have been demonstrated to possess miscellaneous health benefits which are, at least partly, associated with iron chelation. In this in vitro study, 26 flavonoids from different subclasses were analyzed for their iron chelating activity and stability of the formed
[Microbial kinetics: experiences with Staphylococcus aureus ATCC 25 293 and bacteriostatic drugs].
N B Pappano et al.
Revista latinoamericana de microbiologia, 29(4), 367-372 (1987-10-01)
Samir Yahiaoui et al.
Bioorganic & medicinal chemistry, 16(3), 1474-1480 (2007-11-29)
Some natural compounds such as flavonoids are known to possess a moderate inhibitory activity against aromatase, this enzyme being an interesting target for hormone-dependent breast cancer treatment. It has been demonstrated that the modulation of flavonoid skeleton could increase anti-aromatase
Sunhee Lee et al.
Bioorganic & medicinal chemistry letters, 19(8), 2116-2120 (2009-03-25)
To identify the structural requirements that are pivotal in enhancing Early growth response-1 (Egr-1) expression, the quantitative relationships between the structural properties of flavanone derivatives and their increments of Egr-1 expression were elucidated using comparative molecular field analysis and comparative
Edyta Kostrzewa-Susłow et al.
TheScientificWorldJournal, 2012, 254929-254929 (2012-06-02)
Microbial transformations of racemic 7-hydroxyflavanone using strains of genus Aspergillus (A. niger KB, A. niger 13/5, A. ochraceus 456) and the species Penicillium chermesinum 113 were studied. The products of O-methylation, O-methylation along with hydroxylation at C-3' and C-4', reduction

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