H4155
7-Hydroxyflavanone
Synonym(s):
7-Hydroxy-2-phenylchroman-4-one
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About This Item
Empirical Formula (Hill Notation):
C15H12O3
CAS Number:
Molecular Weight:
240.25
UNSPSC Code:
12352100
MDL number:
InChI key
SWAJPHCXKPCPQZ-UHFFFAOYSA-N
InChI
1S/C15H12O3/c16-11-6-7-12-13(17)9-14(18-15(12)8-11)10-4-2-1-3-5-10/h1-8,14,16H,9H2
SMILES string
Oc1ccc2C(=O)CC(Oc2c1)c3ccccc3
mp
188-190 °C (lit.)
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Samir Yahiaoui et al.
Bioorganic & medicinal chemistry, 16(3), 1474-1480 (2007-11-29)
Some natural compounds such as flavonoids are known to possess a moderate inhibitory activity against aromatase, this enzyme being an interesting target for hormone-dependent breast cancer treatment. It has been demonstrated that the modulation of flavonoid skeleton could increase anti-aromatase
[Microbial kinetics: experiences with Staphylococcus aureus ATCC 25 293 and bacteriostatic drugs].
N B Pappano et al.
Revista latinoamericana de microbiologia, 29(4), 367-372 (1987-10-01)
Přemysl Mladěnka et al.
Journal of inorganic biochemistry, 105(5), 693-701 (2011-04-01)
Flavonoids have been demonstrated to possess miscellaneous health benefits which are, at least partly, associated with iron chelation. In this in vitro study, 26 flavonoids from different subclasses were analyzed for their iron chelating activity and stability of the formed
Julie Rakel Mikell et al.
Chemical & pharmaceutical bulletin, 60(9), 1139-1145 (2012-09-15)
Microbial metabolism of 7-hydroxyflavanone (1) with fungal culture Cunninghamella blakesleeana (ATCC 8688a), yielded flavanone 7-sulfate (2), 7,4'-dihydroxyflavanone (3), 6,7-dihydroxyflavanone (4), 6-hydroxyflavanone 7-sulfate (5), and 7-hydroxyflavanone 6-sulfate (6). Mortierella zonata (ATCC 13309) also transformed 1 to metabolites 2 and 3 as
Edyta Kostrzewa-Susłow et al.
TheScientificWorldJournal, 2012, 254929-254929 (2012-06-02)
Microbial transformations of racemic 7-hydroxyflavanone using strains of genus Aspergillus (A. niger KB, A. niger 13/5, A. ochraceus 456) and the species Penicillium chermesinum 113 were studied. The products of O-methylation, O-methylation along with hydroxylation at C-3' and C-4', reduction
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