Name: Hydroxyethyl starch
Brand: SIGMA

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About This Item

CAS Number:

9005-27-0

MDL number:

MFCD00131356

UNSPSC Code:

12352201

PubChem Substance ID:

24895739

NACRES:

NA.25

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biological source

maize

form

powder

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O.OCCOC[C@H]2O[C@H](OCCO)[C@H](OCCO)[C@@H](OCCO)[C@@H]2OCCO

InChI

1S/C16H32O11.C6H12O6/c17-1-6-22-11-12-13(23-7-2-18)14(24-8-3-19)15(25-9-4-20)16(27-12)26-10-5-21;7-1-2-3(8)4(9)5(10)6(11)12-2/h12-21H,1-11H2;2-11H,1H2/t12-,13-,14+,15-,16+;2-,3-,4+,5-,6+/m11/s1

InChI key

DNZMDASEFMLYBU-RNBXVSKKSA-N

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General description

Hydroxyethyl starch is a non-ionic starch derivative. It is categorized based on its in vitro molecular weight. A 6% concentration is commonly preferred with 130 kD and 0.38 to 0.45 of molecular weight and molar substitution ratios respectively. Degree of substitution; Average of 1 ^-OH group per 10 glucose units converted to ^-OCH₂CH₂OH.

Application

Hydroxyethyl starch has been used to study its shear response. It has also been used as a macromolecular compound in the medium for sperm isolation, culture and cryopreservation.

Biochem/physiol Actions

Hydroxyethyl starch (HES) is a colloid used for medicinal practices that involve fluid replacement. It acts as a plasma substitute. Acute kidney failure risk is increased by the use of HES in patients with severe sepsis.

Linkage

The similar Hetastarch (q.v.) is substituted to the extent of 7-8 groups per 10 glucose units.

Preparation Note

Prepared from corn starch

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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