H6515
L-Homoserine
Synonym(s):
(S)-2-Amino-4-hydroxybutyric acid, Hse
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About This Item
Linear Formula:
HOCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
119.12
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
211-590-6
MDL number:
Beilstein/REAXYS Number:
1721681
assay
≥98% (TLC)
Quality Level
form
powder
color
white to off-white
mp
203 °C (dec.) (lit.)
application(s)
cell analysis
detection
SMILES string
N[C@@H](CCO)C(O)=O
InChI
1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1
InChI key
UKAUYVFTDYCKQA-VKHMYHEASA-N
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General description
L-Homoserine is a variant of serine with an additional carbon on its side chain.
Application
L-Homoserine has been used as an internal standard for neurotransmitter analysis and amino acids quantification.
Biochem/physiol Actions
L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.
L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Neurotoxic effect of maneb in rats as studied by neurochemical and immunohistochemical parameters
Nielsen BS, et al.
Environmental Toxicology and Pharmacology, 21(3), 268-275 (2006)
Chiral recognition of non-natural ?-amino acids
Gal JF, et al.
International Journal of Mass Spectrometry, 222(1?3), 259-267 (2003)
Reprogramming Microbial Metabolic Pathways, 288-288 (2012)
Hsuan-Chen Wu et al.
Molecular systems biology, 9, 636-636 (2013-01-24)
Escherichia coli were genetically modified to enable programmed motility, sensing, and actuation based on the density of features on nearby surfaces. Then, based on calculated feature density, these cells expressed marker proteins to indicate phenotypic response. Specifically, site-specific synthesis of
D C Turnell et al.
Clinical chemistry, 28(3), 527-531 (1982-03-01)
This method for estimating clinically important amino acids in serum or urine within 40 min involves o-phthalaldehyde/2-mercaptoethanol derivatization and reversed-phase "high-pressure" liquid chromatography. Homocysteic acid is an internal standard, and homoserine and norvaline are reference peaks. For all the amino
Global Trade Item Number
| SKU | GTIN |
|---|---|
| H6515-5G | 04061832722696 |
| H6515-10MG | 04061833801253 |
| H6515-250MG | 04061833801390 |
| H6515-1G | 04061826212226 |
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