H7160
Hepatitis C virus core antigen−Fluorescein
~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
recombinant
expressed in E. coli
assay
≥95% (SDS-PAGE)
mol wt
22 kDa (plus 114 kDa β-Gal tag)
concentration
~1 mg/mL
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Quality Level
Gene Information
hepatitis C virus ... HCVgp1(951475)
Biochem/physiol Actions
Positive control for HCV antibodies.
Physical form
Solution in 1.2 M Urea, 20 mM Tris-HCl, pH 8.0, 10 mM 2-mercaptoethanol.
Other Notes
HCV core antigen [2-192]-Galactosidase-tagged, fluorescein conjugate.
Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
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Inés Romero-Brey et al.
mBio, 6(4), e00759-e00759 (2015-07-15)
Induction of membrane rearrangements in the cytoplasm of infected cells is a hallmark of positive-strand RNA viruses. These altered membranes serve as scaffolds for the assembly of viral replication factories (RFs). We have recently shown that hepatitis C virus (HCV)
Margaret A Scull et al.
PLoS pathogens, 11(11), e1005297-e1005297 (2015-11-21)
The hepatitis C virus (HCV) p7 protein is required for infectious virus production via its role in assembly and ion channel activity. Although NMR structures of p7 have been reported, the location of secondary structural elements and orientation of the
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