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Merck
CN

H8409

Hymenistatin I

>99% (HPLC)

Synonym(s):

HS-1

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About This Item

Empirical Formula (Hill Notation):
C47H72N8O9
Molecular Weight:
893.12
UNSPSC Code:
12352200
PubChem Substance ID:
329815251
MDL number:
MFCD00909204

Key Documents

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InChI

1S/C47H72N8O9/c1-9-27(6)37-43(60)51-38(28(7)10-2)44(61)52-39(29(8)11-3)47(64)55-24-14-17-35(55)45(62)53-22-12-15-33(53)41(58)48-32(25-30-18-20-31(56)21-19-30)40(57)49-36(26(4)5)46(63)54-23-13-16-34(54)42(59)50-37/h18-21,26-29,32-39,56H,9-17,22-25H2,1-8H3,(H,48,58)(H,49,57)(H,50,59)(H,51,60)(H,52,61)/t27-,28-,29-,32-,33-,34-,35-,36-,37-,38-,39-/m0/s1

SMILES string

CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]4CCCN4C(=O)[C@@H]5CCCN5C(=O)[C@@H](NC(=O)[C@@H](NC1=O)[C@@H](C)CC)[C@@H](C)CC)C(C)C

InChI key

GEELDTSKBDMDCJ-GDLJMZEHSA-N

assay

>99% (HPLC)

storage temp.

−20°C

Quality Level

200

Biochem/physiol Actions

Exerts an immunosuppressive effect on humoral and cellular immune responses similar to cyclosporin A.
Immunosuppessant.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
110M1513
091K1288
091K1287

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X Gong et al.
Nature communications, 10(1), 656-656 (2019-02-10)
The deglacial history of CO2 release from the deep North Pacific remains unresolved. This is due to conflicting indications about subarctic Pacific ventilation changes based on various marine proxies, especially for Heinrich Stadial 1 (HS-1) when a rapid atmospheric CO2
Maryam Ravaghi et al.
Food chemistry, 220, 233-241 (2016-11-20)
In this study, canthaxanthin (CTX) was produced by Dietzia natronolimnaea HS-1 using beetroot molasses as substrate and used for encapsulation in proniosome powders after extraction, with the aim of improving its stability. Proniosome powders were prepared with an equimolar ratio
Ke Tian et al.
OncoTargets and therapy, 13, 1277-1287 (2020-02-28)
Although X-inactive specific transcript (XIST) is known to play a critical role in the pathogenesis of melanoma, the mechanisms through which this remains unclear. RNAseq, immunohistochemistry, and qRT-PCR were used to identify the levels of XIST, miR-139-5p, and Rho-Associated Coiled-Coil

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