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Merck
CN

H8771

1-O-Palmityl-2-acetyl-sn-glycero-3-phospho-(N,N,N-trimethyl)hexanolamine

~95%

Synonym(s):

L-α-Phosphatidyl[N,N,N-trimethyl]hexanolamine, β-acetyl, γ-hexadecyl

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About This Item

Empirical Formula (Hill Notation):
C30H62NO7P
CAS Number:
Molecular Weight:
579.79
UNSPSC Code:
12352211
PubChem Substance ID:
MDL number:
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InChI

1S/C32H67NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-27-37-29-32(40-31(2)34)30-39-41(35,36)38-28-25-22-20-23-26-33(3,4)5/h32H,6-30H2,1-5H3,(H,35,36)

SMILES string

CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(=O)OCCCCCC[N](C)(C)C)OC(C)=O

InChI key

HRYXIYMPLGFZGG-UHFFFAOYSA-N

assay

~95%

form

solid

functional group

amine

shipped in

ambient

storage temp.

−20°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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H Homma et al.
The Journal of biological chemistry, 262(22), 10582-10587 (1987-08-05)
The binding profile of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (AGEPC, platelet-activating factor) to washed rabbit platelets was investigated through the use of structural analogs of AGEPC, e.g. U66985, which specifically suppressed AGEPC biological activities on rabbit platelets. This interaction of AGEPC with platelets could
[Antagonists of platelet activating factor].
A Tokumura et al.
Seikagaku. The Journal of Japanese Biochemical Society, 57(12), 1618-1623 (1985-12-01)
E G Vornovitskiĭ et al.
Biulleten' eksperimental'noi biologii i meditsiny, 108(8), 137-139 (1989-08-01)
The effects of platelet activating factor (PAF) and three its antagonists on the transmembrane intracellular potentials and stimulated (0.5 Hz) contraction amplitude (CA) of the left auricle has been studied. PAF (1-5 X 10(-7) M) was added to the standard
E G Vornovitskiĭ et al.
Biulleten' eksperimental'noi biologii i meditsiny, 108(12), 643-646 (1989-12-01)
The effects of platelet-activating factor (PAF) on the myocardial cell membrane Ca-current (ICa) and Ca-action potential (Ca-AP) were investigated. In double sucrose-gap voltage-clamped frog atrial trabeculae PAF (2 X 10(-7) M) reduced ICa-amplitude to 40-50%; at the same time the
M Gollasch et al.
Journal of lipid mediators, 3(2), 139-159 (1991-03-01)
The effects of platelet-activating factor (PAF) on intracellular action potentials and isometric contractions of guinea-pig auricle muscle and ionic currents of frog atrial trabeculae were investigated. Experiments to study the effects of PAF on ionic currents in nerve fibre membrane

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