H9000
His-Gly
Synonym(s):
histidylglycine
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About This Item
Empirical Formula (Hill Notation):
C8H12N4O3
CAS Number:
Molecular Weight:
212.21
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
NC(Cc1cnc[nH]1)C(=O)NCC(O)=O
storage temp.
−20°C
Biochem/physiol Actions
Histidylleucine (His-Leu); histidylglycine (His-Gly) and histidylserine (His-Ser) are N-terminal imidazole containing dipeptides used to study binding of metals such as copper, nickel and zinc.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Zorica D Petrović et al.
Dalton transactions (Cambridge, England : 2003), 40(36), 9284-9288 (2011-08-13)
The reaction of K(2)PtCl(4) with the alkylating agent mechlorethamine hydrochloride, at a molar ratio of 1:2, results in the formation of 2-chloro-N-(2-chloroethyl)-N-methylethylammonium-tetrachloridoplatinate(II) complex. The hydrolytic activity of the novel Pt(II) complex was tested in the reaction with N-acetylated L-histidylglycine dipeptide
M A Hefford et al.
Biochimica et biophysica acta, 998(3), 267-270 (1989-10-19)
Secretin has a single histidine residue located at the amino terminus which plays a crucial role in its biological activity. The chemical properties, viz. pK and reactivity, of the alpha-amino and imidazole groups of this residue were determined at a
G Kilian et al.
Die Pharmazie, 68(3), 207-211 (2013-04-06)
Cyclic dipeptides have been well characterized for their biological activity, including antimicrobial and anticancer activities. Cyclo(His-Gly) and cyclo(His-Ala) have also recently demonstrated significant anticancer activity against a range of cell lines, however, as a result of their physicochemistry, namely high
Brandon I Macdonald et al.
Rapid communications in mass spectrometry : RCM, 22(18), 2946-2954 (2008-08-30)
Pathways for proton transfer in the histidylglycine cation are examined in the gas-phase environment with the goal of understanding the mechanism by which protons may become mobile in proteins with basic amino acid residues. An extensive search of the potential
Terézia Szabó-Plánka et al.
Inorganic chemistry, 41(13), 3483-3490 (2002-06-25)
Twelve ESR-active (and one inactive) copper(II) complexes of L-histidylglycine (HL) were characterized via their formation (micro)constants and ESR parameters obtained by two-dimensional ESR spectroscopic evaluation in aqueous solution. In strongly acidic media, the ligand is coordinated through its N-terminal donor
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