H9000
His-Gly
Synonym(s):
histidylglycine
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About This Item
Empirical Formula (Hill Notation):
C8H12N4O3
CAS Number:
Molecular Weight:
212.21
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
storage temp.
−20°C
SMILES string
NC(Cc1cnc[nH]1)C(=O)NCC(O)=O
Biochem/physiol Actions
Histidylleucine (His-Leu); histidylglycine (His-Gly) and histidylserine (His-Ser) are N-terminal imidazole containing dipeptides used to study binding of metals such as copper, nickel and zinc.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Anoja P Wickrama Arachchilage et al.
The Journal of chemical physics, 136(12), 124301-124301 (2012-04-03)
We have investigated the electronic structure of three cyclic dipeptides: cyclo(Histidyl-Glycyl) (cHisGly), cyclo(Tyrosyl-Prolyl) (cTyrPro), and cyclo(Phenylalanyl-Phenylalanyl) (cPhePhe) in the vapor phase, by means of photoemission spectroscopy and theoretical modeling. The last compound was evaporated from the solid linear dipeptide, but
Zorica D Petrović et al.
Bioorganic chemistry, 34(5), 225-234 (2006-08-08)
The reaction of PdCl2, or K2PdCl4, with diethanolamine (DEA), in the molar ratio 1:2, affords the trans-[PdCl2(DEA)2] complex. X-ray structure analysis of this complex confirmed the formation of the trans-isomer. The complex crystallizes in the space group P42bc. The central
G Kilian et al.
Die Pharmazie, 68(3), 207-211 (2013-04-06)
Cyclic dipeptides have been well characterized for their biological activity, including antimicrobial and anticancer activities. Cyclo(His-Gly) and cyclo(His-Ala) have also recently demonstrated significant anticancer activity against a range of cell lines, however, as a result of their physicochemistry, namely high
Zorica D Petrović et al.
Dalton transactions (Cambridge, England : 2003), 40(36), 9284-9288 (2011-08-13)
The reaction of K(2)PtCl(4) with the alkylating agent mechlorethamine hydrochloride, at a molar ratio of 1:2, results in the formation of 2-chloro-N-(2-chloroethyl)-N-methylethylammonium-tetrachloridoplatinate(II) complex. The hydrolytic activity of the novel Pt(II) complex was tested in the reaction with N-acetylated L-histidylglycine dipeptide
M A Hefford et al.
Biochimica et biophysica acta, 998(3), 267-270 (1989-10-19)
Secretin has a single histidine residue located at the amino terminus which plays a crucial role in its biological activity. The chemical properties, viz. pK and reactivity, of the alpha-amino and imidazole groups of this residue were determined at a
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