H9160
Hydroxystilbamidine bis(methanesulfonate)
Synonym(s):
2-Hydroxystilbene-4,4′-dicarboxamidine bis(methanesulfonate)
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About This Item
Empirical Formula (Hill Notation):
C18H24N4O7S2
CAS Number:
Molecular Weight:
472.54
PubChem Substance ID:
MDL number:
InChI key
YGNSQKCULHSJDC-HFPMQDOPSA-N
InChI
1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;
SMILES string
CS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)\C=C\c2ccc(cc2O)C(N)=N
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Eva Placheta et al.
Neuroscience letters, 582, 81-86 (2014-09-16)
Accumulating evidence suggests that neuregulin, a potent Schwann cell mitogen, and its receptor, ErbB2, have an important role in regulating peripheral nerve regeneration. We hypothesized that Herceptin (Trastuzumab), a monoclonal antibody that binds ErbB2, would disrupt ErbB2 signaling, allowing us
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