H9285
Heat Shock Factor 1 human
recombinant, expressed in E. coli, ~65% (SDS-PAGE), solution
Synonym(s):
HSF-1, Heat Shock Transcription Factor 1
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About This Item
UNSPSC Code:
12352204
MDL number:
biological source
human
recombinant
expressed in E. coli
form
solution
concentration
~65% (SDS-PAGE)
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... HSF1(3297)
Biochem/physiol Actions
A transcriptional factor that mediates the expression of heat shock proteins by binding to a heat shock response element located upstream from the heat shock protein genes. In unstressed cells HSF-1 is non-DNA binding protein that rapidly converts to the transcriptionally active form in response to heat and heavy metals.
Physical form
in 25 mM Tris pH 8.0, 150 mM NaCl, 2 mM DTT
Regulatory Information
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K D Sarge et al.
Molecular and cellular biology, 13(3), 1392-1407 (1993-03-01)
The existence of multiple heat shock factor (HSF) genes in higher eukaryotes has promoted questions regarding the functions of these HSF family members, especially with respect to the stress response. To address these questions, we have used polyclonal antisera raised
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