I0904
Interleukin-2 Soluble Receptor β human
>97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder
Synonym(s):
IL-2 sRα
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About This Item
UNSPSC Code:
51111800
MDL number:
biological source
human
recombinant
expressed in baculovirus infected Sf21 cells
assay
>97% (SDS-PAGE)
form
lyophilized powder
mol wt
predicted mol wt ~25 kDa
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... IL2RB(3560)
Biochem/physiol Actions
Recombinant human IL-2 soluble receptor β is a member of the cytokine receptor superfamily. It binds IL-2 with low affinity but will bind IL-15 sufficiently for neutralization activities.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.
Analysis Note
The bioactivity is measured by its ability to inhibit the IL-15-dependent proliferation of a human megakaryocytic leukemic cell line, M07e.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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G C Avanzi et al.
British journal of haematology, 69(3), 359-366 (1988-07-01)
A new human leukaemic cell line (M-O7) with the phenotypic characteristics of CFU-mega is described. Its cells are positive for T200 leucocyte common antigen (LCA) and negative with MAbs recognizing T and B cells and mature myelomonocytic antigens. In contrast
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