biological source
human
recombinant
expressed in baculovirus infected Sf21 cells
Assay
>97% (SDS-PAGE)
form
lyophilized powder
potency
1.979 μg/mL ED50
mol wt
40 kDa
packaging
pkg of 50 μg
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... IL2RG(3561)
General description
IL2RG (Interleukin-2 soluble receptor γ) is a type I transmembrane glycoprotein. It is a component of interleukin (IL)-receptors, including IL-2, IL-7, IL-9, IL-15 and IL-21.
Biochem/physiol Actions
IL2RG (Interleukin-2 soluble receptor γ) controls JAK3 (Janus kinase 3) signalling in ligand-dependent manner. Expression of IL2RG mRNA is upregulated in peripheral blood of humans suffering from schizophrenia. Mutations in IL2RG are associated with X-linked severe combined immunodeficiency, due to disturbances in function of cytokine receptors.
Recombinant human IL-2 soluble receptor γ is a member of the hematopoietin receptor family and is required for IL-2 receptor signaling.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 2.5 mg bovine serum albumin.
Analysis Note
The bioactivity is measured by its ability to inhibit the IL-2-dependent proliferation of a human megakaryocytic leukemic cell line, MO7e, in the presence of 30 μg/ml of soluble IL-2 Rγ.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service