I1909
Immethridine hydrobromide
≥98% (HPLC), solid
Synonym(s):
4-(1H-Imidazol-4-ylmethyl)pyridine hydrobromide
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About This Item
Empirical Formula (Hill Notation):
C9H9N3 · xHBr
CAS Number:
Molecular Weight:
159.19 (free base basis)
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C9H9N3.BrH/c1-3-10-4-2-8(1)5-9-6-11-7-12-9;/h1-4,6-7H,5H2,(H,11,12);1H
SMILES string
Br[H].C(c1ccncc1)c2c[nH]cn2
InChI key
XAOXYOKDVRPLBH-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
solid
color
off-white
solubility
DMSO: ~10 mg/mL, H2O: insoluble
Biochem/physiol Actions
Potent, highly selective H3 histamine receptor agonist
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Ruengwit Kitbunnadaj et al.
Journal of medicinal chemistry, 47(10), 2414-2417 (2004-04-30)
In this study, the piperidine ring of immepip and its analogues was replaced by a rigid heterocyclic pyridine ring. Many compounds in the series exhibit high affinity and agonist activity at the human histamine H(3) receptor. Particularly, the 4-pyridinyl analogue
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