I2656
Insulin-like Growth Factor-I (E3R) human
>95% (HPLC), recombinant, expressed in E. coli, lyophilized powder
Synonym(s):
IGF-I (E3R)
biological source
human
recombinant
expressed in E. coli
assay
>95% (HPLC)
form
lyophilized powder
mol wt
7.6 kDa
UniProt accession no.
storage temp.
2-8°C
Gene Information
human ... IGF1(3479)
Biochem/physiol Actions
IGF1(3R) contains the amino acid substitution E3R, which decreases binding to IGF-binding proteins. IGF1(3R) therefore is much more potent than the native IFG1.
Physical form
Lyophilzed from a solution in 0.1 M acetic acid.
Analysis Note
The biological activity is assayed using L6 myoblasts.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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D LeRoith et al.
Annals of the New York Academy of Sciences, 692, 1-9 (1993-08-27)
The purpose of this review has been to emphasize, in general terms, the major aspects of the structure, expression, and regulation of the IGF-I and IGF-II genes. The complex organization of these genes provides ample opportunities for control of gene
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