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Merck
CN

I3771

Ile-Tyr-Pro-Arg-Tyr

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C35H50N8O8
CAS Number:
Molecular Weight:
710.82
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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Assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC[C@H](C)[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc3ccc(O)cc3)C(O)=O

Biochem/physiol Actions

ACE inhibiting peptide that reduces blood pressure in hypertensive rats.

Regulatory Information

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Y Saito et al.
Bioscience, biotechnology, and biochemistry, 58(10), 1767-1771 (1994-10-01)
Nine peptides to inhibit angiotensin I converting enzyme (ACE) were isolated from sake and sake lees. They were short peptides with 5 or fewer amino acid residues, and many of them had a tryptophan or tyrosine residue at the C-terminus.

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