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Merck
CN

I3903

Monoclonal Anti-Interleukin-6 antibody produced in mouse

clone 53325.111, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-IL-6

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About This Item

UNSPSC Code:
51111800
MDL number:
Technical Service
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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

53325.111, monoclonal

form

lyophilized powder

species reactivity

rat

technique(s)

capture ELISA: suitable using a recombinant rat IL-6

isotype

IgG2b

storage temp.

−20°C

Immunogen

recombinant rat IL-6 expressed in Escherichia coli.

Physical form

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline.

Preparation Note

Purified using protein G.

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Constantina A Pappa et al.
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Current opinion in infectious diseases, 33(1), 34-43 (2019-12-04)
To evaluate the current scientific basis for administering probiotics to people living with HIV (PLHIV) to alleviate chronic inflammation and subsequently improve their prognosis. The gut microbiome is a potential contributing factor to low-grade inflammation in HIV infection, and there
Chun-Hsien Chu et al.
Journal of cellular physiology, 227(1), 259-268 (2011-03-18)
The IGF-II/mannose 6-phosphate receptor (IGF-IIR/Man-6-P) up-regulation correlates with heart disease progression and its signaling cascades directly trigger pathological cardiac hypertrophy, fibrosis, and cardiomyocytes apoptosis. IGF-IIR gene expression/ suppression is able to prevent myocardial remodeling. However, the regulating mechanisms for the
J Niu et al.
Clinical and experimental immunology, 176(3), 473-484 (2014-02-18)
Hepatic allograft rejection remains a challenging problem, with acute rejection episode as the major barrier for long-term survival in liver transplant recipients. To explore a strategy to prevent allograft rejection, we hypothesized that mesenchymal stem cells (MSCs) genetically engineered with
Hagen Maxeiner et al.
Journal of cellular physiology, 229(11), 1681-1689 (2014-03-14)
Cardiosphere-derived cells (CDCs) were cultured from human, murine, and rat hearts. Diluted supernatant (conditioned-medium) of the cultures improved the contractile behavior of isolated rat cardiomyocytes (CMCs). This effect is mediated by the paracrine release of cytokines. The present study tested

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