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I5277

Interferon-γ Receptor 1 human

Name: Interferon-γ Receptor 1 human
Brand: SIGMA

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym(s):

IFN-γ R 1

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About This Item

UNSPSC Code:

51111800

MDL number:

MFCD03457243

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Properties

biological source

human

recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

potency

1-3 μg/mL ED₅₀

mol wt

glycosylated form 40-50 kDa by electrophoresis

storage condition

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

impurities

endotoxin, tested

UniProt accession no.

P15260

storage temp.

−20°C

Gene Information

human ... IFNGR1(3459)

Description

Biochem/physiol Actions

Recombinant human IFN-γ receptors are comprised of two type I membrane proteins, IFN-γ R1 and IFN-γ R2. Both are members of the type II cytokine receptor family. IFN-γ R1 binds IFN-γ ligand and is a potent IFN-γ antagonist.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5.0 mg bovine serum albumin.

Analysis Note

The bioactivity is measured by its ability to inhibit recombinant human IFN-γ mediated protection of Hela cells to viral lysis.

Other Notes

Mouse and human IFN-γ share 52% homology.

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

100K0062

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