I7389
Interleukin-3 human
IL-3, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Synonym(s):
hIL-3, IL-3
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About This Item
Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥95% (SDS-PAGE)
Form:
lyophilized powder
Impurities:
<0.1 EU/μg
biological source
human
Quality Segment
recombinant
expressed in E. coli
assay
≥95% (SDS-PAGE)
form
lyophilized powder
potency
<0.5 ng/mL ED50
quality
endotoxin tested
packaging
pkg of 4 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 EU/μg
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Interleukin-3 (IL-3) is a multifunctional protein, originally called colony forming unit-stimulating activity (CFU-SA), and is produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 has been shown to induce colony formation of macrophages, neutrophils, mast cells, and megakaryocytes from agar-suspended bone marrow cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and to induce IgG secretion from activated B cells. Other synonyms for IL-3 include pan-specific hemopoietin, multicolony stimulating factor, mast cell growth factor, burst promoting activity, histamine-producing cell stimulating factor, P cell stimulating factor, and WEHI-3 factor.
Interleukin-3 is a multifunctional protein produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and induce IgG secretion from activated B cells.
Physical form
Lyophilized from a 0.2 μm filtered solution.
Other Notes
One unit is the amount of IL-3 required to induce half-maximal incorportion of 3H thymidine. Activity also is expressed in Reference units (NIBSC reference preparation for IL-3 code 88/87).
Storage Class
12 - Non Combustible Liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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