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Merck
CN

I7658

Sigma-Aldrich

Anti-phospho-Integrin β3 (pTyr785) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~130 kDa

species reactivity

mouse, human, rat

technique(s)

western blot: 0.1-1.0 μg/mL using K562 cells transfected with human Integrin αv and wild-type (WT) or mutant (Tyr785F)

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... ITGB3(3690)
mouse ... Itgb3(16416)
rat ... Itgb3(29302)

Immunogen

synthetic phosphopeptide derived from C-terminus of the integrin β3 receptor that contains tyrosine 785. The sequence is conserved in human, mouse, and rat.

Physical form

Solution in phosphate buffer, pH 7.4 containing 1 mg/mL BSA (protease and IgG-free) and 0.05% sodium azide.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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D D Schlaepfer et al.
Trends in cell biology, 8(4), 151-157 (1998-08-08)
The integrin family of transmembrane receptors have long been recognized for their structural roles in linking extracellular matrix proteins with the cellular actin cytoskeleton to regulate cell shape, cell migration and tissue architecture. Lately, it has become clear that integrin

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