I8641
Inhibin α-Subunit Fragment 1-32 porcine
≥90% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C163H248N48O43S
CAS Number:
Molecular Weight:
3600.07
UNSPSC Code:
51111800
MDL number:
biological source
Porcine
assay
≥90% (HPLC)
form
powder
composition
Peptide content, ~60%
color
white
solubility
water: soluble 1 mg/mL, clear, colorless
storage temp.
−20°C
Application
An immunogenic fragment of inhibin.
Inhibin α-subunit fragment 1-32 porcine has been used in the ELISA (enzyme-linked immunosorbent assay) for detection of the inhibin antibody levels.
Biochem/physiol Actions
Inhibins are glycoproteins made of an α subunit and a β subunit. They suppress FSH (follicle stimulating hormone) secretion from the pituitary and also participate in control of gonadal functions. Inhibin α (INHA) is present in adrenal glands, pituitary gland, liver and placenta. It plays a significant role in male fertility.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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A J Mason et al.
Nature, 318(6047), 659-663 (1985-12-19)
Inhibin, a specific and potent polypeptide inhibitor of the secretion of follicle-stimulating hormone (FSH), of gonadal origin and thus a potential contraceptive, may constitute a missing link in the mechanism controlling the differential secretion of the pituitary gonadotropins. Inhibin-like bioactivity
F M Hui et al.
Genetics and molecular research : GMR, 13(3), 6113-6125 (2014-08-15)
DNA vaccination has been studied intensively as a potential vaccine technology. We evaluated the effect of an attenuated Salmonella choleraesuis-mediated inhibin DNA vaccine in rats. First, 15 rats were treated with different doses of an inhibin vaccine to evaluate vaccine
Pawel Walentowicz et al.
PloS one, 9(3), e90575-e90575 (2014-03-07)
of our study was to examine serum inhibin A and inhibin B concentrations in ovarian cancer patients in relation to clinicopathological features and 5-year survival. We enrolled 90 epithelial ovarian cancer patients in our study, aged 45-81 years, who underwent